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Predictive Risk Analytics & Early Alert
System for a Global Pharma Major

100,000
employees worldwide

€47.6 billion
in global sales

291
subsidiaries in 80 countries

160 + years
of pharmaceutical & science leadership

Business Case

The client held millions of trial, lab, and EHR records but no single view to run predictive risk analytics. The gap slowed their AI in healthcare push and let early warning signs slip past care teams. It faced certain issues like:

Fragmented Inputs

Vital signs, lab results, and trial data lived in separate siloes making doctors ignorant about cross-source trends in time

Fuzzy Definitions

“Positive” patient labels varied by unit and study indicated lack of clear rules causing noisy training targets

Class Imbalance

Only ~4 % of records showed early signs of decline featuring standard models that over-fit to the safe majority

Impact Delivered

150+ vital-sign features

Early alert system flags high-risk patients ~180 days sooner

17% drop in pilot
sites

Fewer emergencies and unplanned ER visits within six months

8 million patient records cleaned and merged

Ensured end-to-end lineage and systematic audit logs

Our Solution

We built a cloud data hub that pulls trial, lab, and EHR records into one stream, ready for agentic AI agents to scan in near real time. We also trained a risk model that fuels an early alert system, sending care teams clear flags up to six months before trouble hits

Data preparation

We standardized units, aligned IDs, and filled important gaps to give the model clean, consistent inputs.

Handling missing data

Sound statistical methods replaced blanks, keeping key signals intact while avoiding bias.

Balancing rare events

We adjusted training samples so early-risk cases stayed visible, improving the model’s sensitivity.

Feature engineering

Rate-of-change, rolling average, and trend indicators captured subtle shifts in patient status.

Model development

An iteratively tuned ensemble found patterns that generalize well to new patients.

Interpretability layer

Clear factor-importance views help clinicians see why each alert fires.

Validation

Cross-validation plus a reserved test set confirmed strength before rollout.

Tech Stack

PostgreSQL

Python

AWS