Predictive Risk Analytics & Early Alert
System for a Global Pharma Major
100,000
employees worldwide
€47.6 billion
in global sales
291
subsidiaries in 80 countries
160 + years
of pharmaceutical & science leadership
Business Case
The client held millions of trial, lab, and EHR records but no single view to run predictive risk analytics. The gap slowed their AI in healthcare push and let early warning signs slip past care teams. It faced certain issues like:
Fragmented Inputs
Vital signs, lab results, and trial data lived in separate siloes making doctors ignorant about cross-source trends in time
Fuzzy Definitions
“Positive” patient labels varied by unit and study indicated lack of clear rules causing noisy training targets
Class Imbalance
Only ~4 % of records showed early signs of decline featuring standard models that over-fit to the safe majority
150+ vital-sign features
Early alert system flags high-risk patients ~180 days sooner
17% drop in pilot
sites
Fewer emergencies and unplanned ER visits within six months
8 million patient records cleaned and merged
Ensured end-to-end lineage and systematic audit logs
Our Solution
We built a cloud data hub that pulls trial, lab, and EHR records into one stream, ready for agentic AI agents to scan in near real time. We also trained a risk model that fuels an early alert system, sending care teams clear flags up to six months before trouble hits
Data preparation
We standardized units, aligned IDs, and filled important gaps to give the model clean, consistent inputs.
Handling missing data
Sound statistical methods replaced blanks, keeping key signals intact while avoiding bias.
Balancing rare events
We adjusted training samples so early-risk cases stayed visible, improving the model’s sensitivity.
Feature engineering
Rate-of-change, rolling average, and trend indicators captured subtle shifts in patient status.
Model development
An iteratively tuned ensemble found patterns that generalize well to new patients.
Interpretability layer
Clear factor-importance views help clinicians see why each alert fires.
Validation
Cross-validation plus a reserved test set confirmed strength before rollout.